Dr. Andreazza’s laboratory focuses on the understanding the role of mitochondrial function in mental illness, especially in mood disorders. As neurons depend on mitochondrial function, dysfunctional mitochondrial during neurodevelopment is expected to impact neurotransmission with potentially crucial implications for mood disorders. Dr. Andreazza laboratory works within a range of biochemical and molecular biology technologies. The laboratory is vibrant and collaborative environment. We are searching for an individual with background in human iPSC generation, culture, and development of 2D cell models and 3D brain organoids models to study mitochondrial health (function, genetics and morphology) and development of by-genomic interaction models leading to test of target therapeutics. Ideal candidates must have experience in some or all the below:

QUALIFICATIONS

A minimum of a bachelor’s degree required. Background in iPSC, brain organoids, cell work, mitochondrial biology, and genetics are a strong asset.

Seeking one creative, collaborative individual who will be responsible with assisting in the smooth day-to-day operation of the lab and provide basic laboratory support such as sample preparation, routine assay techniques, and iPSC, 2D and 3D cell technologies. Ideal candidates must have experience in some or all the below:

• Mammalian cell and molecular biology
• Human iPSC generation, colony selection, characterization
• PCR/qPCR
• Designing and generating DNA constructs
• Lineage-directed differentiation
• Brain organoids development
• Biochemical Assays
• Immunofluorescence
• Cell culture
• ELISA/ Colorimetric Assays

Individuals must also:

• Work well in a goal-oriented team environment;
• Have the ability to work independently and organize own workload;
• Strong attention to detail;
• Adaptable and willing to aid in any other laboratory activities

APPLICATION INSTRUCTIONS

The Andreazza laboratory is situated at the Medical Science Building at the University of Toronto, Department of Pharmacology & Toxicology.

The position starts as early as February 2024 and will be based on a 6-month renewable contract. Salary will be commensurate with qualifications and experience. A letter of application, accompanied by a Curriculum vitae, and contact details for 3 references, should be sent by email to:

Ana Andreazza: ana.andreazza@utoronto.ca

Applications will remain open until the positions are filled. Review of applications will begin immediately and continue until the positions are filled.

Equity and diversity are essential to academic excellence. An open and diverse community fosters the inclusion of voices that have been underrepresented or discouraged. We encourage applications from members of groups that have been marginalized. All qualified candidates are encouraged to apply; however, Canadians and permanent residents will be given priority.